My home daily driver includes one. I bought the extra relocatable USB hub for mine. I've mentioned here before that it works for its intended purposes, but like anything, it has pros and cons. One of the unexpected cons I found was that larger motherboards (i.e., ATX or EATX) slightly overlap the right (back) radiator if you have such a thing installed. In the traditional setup, this would be the side where wires plug into the motherboard, thus slightly impeding airflow through a 360mm radiator. It isn't much, but it is there if that is a deal breaker.
Also, I found that once I built the setup, I don't think I'm really going to take advantage of the reversible potential. Seems like that would be an initial build decision point and rarely would change except under extenuating circumstances (e.g., having to relocate to a different desk or room setup).
If you have any other questions, I'll be happy to try and answer them.