You could use this for a variety of things - but a NAS / DAS alternative it is not.
This seems like it'd be pretty useful if one needed to access quite a few 3.5" HDDs at one time. Could be useful for occasionally attended replication and so on. Bit of a niche within a niche though - one would almost never be using bare, single 3.5" HDDs to store data, and if they did, they'd likely not need to have up to ten connected at once.
Now, for the sake of experimentation, one could absolutely say load up FreeNAS (or more likely TrueNAS Scale, based on Debian) and set up a ZFS array on one of these. Could even pass the device through to a VM running a ZFS-capable OS and do the same - I have seen things.
But this would still only really be useful for extremely niche circumstances. Performance is likely to be terrible when accessing more than one drive simultaneously, but a ZFS array is extremely portable and can protect against bitrot.
[and I go back to wondering how the ZFS-on-Windows project is doing...]